Publications

2020

Ghasemian M, Layton C, Nampe D, zur Nieden NI, Tsutsui H, and Princevac M. Hydrodynamic characterization within a spinner flask and a rotary wall vessel for stem cell culture. Biochemical Engineering Journal 2020;157:107533. https://doi.org/10.1016/j.bej.2020.107533

Rutherford D, Exarhos S, Xu C, Niacaris M, Mariano C, Dayap B, Mangolini L, and Liu H. Synthesis, characterization, and cytocompatibility of yttria stabilized zirconia nanopowders for creating a window to the brain. Journal of Biomedical Materials Research Part B: Applied Biomaterials 2020;108:925–38. https://doi.org/10.1002/jbm.b.34445

Leung AW, Broton C, Bogacheva MS, Xiao AZ, Garcia-Castro MI, and Lou YR. RNA-based CRISPR-Mediated Loss-of-Function Mutagenesis in Human Pluripotent Stem Cells. Journal of Molecular Biology Published Online First: 25 April 2020. https://doi.org/10.1016/j.jmb.2020.04.017

Prasad MS, Uribe-Querol E, Marquez J, Vadasz S, Yardley N, Shelar PB, Charney RM, and Garcia-Castro MI. Blastula stage specification of avian neural crest. Developmental Biology 2020;458:64–74. https://doi.org/10.1016/j.ydbio.2019.10.007

Marquez J, Criscione J, Charney RM, Prasad MS, Hwang WY, Mis EK, García-Castro MI, Khokha MK. Disrupted ER membrane protein complex-mediated topogenesis drives congenital neural crest defects. J Clin Invest. 2020 Jan 6. https://www.jci.org/articles/view/129308

Zheng, Sika. Alternative splicing programming of axon formation. WIREs RNA. Jan 2020; e1585. https://doi.org/10.1002/wrna.1585

2019

Davis, B, Vivian To, and PrueTalbot (2019) Comparison of cytotoxicity of IQOS aerosols to smoke from Marlboro Red and 3R4F reference cigarettes. Toxicology In Vitro Vol 61, December 2019, 104652. https://doi.org/10.1016/j.tiv.2019.104652

Christopher B. Horner, Maricela Maldonado, Youyi Tai, R. M. Imtiaz Karim Rony, and Jin Nam. Spatially Regulated Multiphenotypic Differentiation of Stem Cells in 3D via Engineered Mechanical Gradient. ACS Applied Materials & Interfaces 2019 11 (49), 45479-45488. https://pubs.acs.org/doi/10.1021/acsami.9b17266

Prasad MS, Uribe-Querol E, Marquez J, Vadasz S, Yardley N, Shelar PB, Charney RM, García-Castro MI. Blastula stage specification of avian neural crest. Dev Biol. 2019 Oct 11; https://www.sciencedirect.com/science/article/pii/S0012160619303574

Gomez GA, Prasad MS, Wong M, Charney RM, Shelar PB, Sandhu N, Hackland JOS, Hernandez JC, Leung AW, García-Castro MI. WNT/β-catenin modulates the axial identity of embryonic stem cell-derived human neural crest. Development. 2019 Aug 29;146(16). doi: 10.1242/dev.175604.

Hackland JOS, Shelar PB, Sandhu N, Prasad MS, Charney RM, Gomez GA, Frith TJR, García- Castro MI. FGF Modulates the Axial Identity of Trunk hPSC-Derived Neural Crest but Not the Cranial-Trunk Decision. Stem Cell Reports. 2019 May 14;12(5):920-933. doi: 10.1016/j.stemcr.2019.04.015.

Gang Guo, Xiang Zhuang, Qing Xu, Zhenru Wu, Yongjie Zhu, Yongjie Zhou, Yuanmin Li, Yanrong Lu, Bo Zhang, Prue Talbot, Jiayu Liao, Junjun She, Hong Bu & Yujun Shi. Peripheral infusion of human umbilical cord mesenchymal stem cells rescues acute liver failure lethality in monkeys. Stem Cell Res Ther 10, 84 (2019). https://doi.org/10.1186/s13287-019- 1184-2.

Gustavo A. Gomez, Maneeshi S. Prasad, Nabjot Sandhu, Patrick B. Shelar, Alan W. Leung and Martín I. García-Castro. Human neural crest induction by temporal modulation of WNT activation. (2019), Developmental Biology. 449: 99-106. https://www.sciencedirect.com/science/article/pii/S0012160618304548

Maria A. Surmeneva, Anna A. Ivanova, Qiaomu Tian, Rebekah Pittman, Wensen Jiang, Jiajia Lin, Huinan H. Liu, Roman A. Surmenev. Bone marrow derived mesenchymal stem cell response to the RF magnetron sputter deposited hydroxyapatite coating on AZ91 magnesium alloy. (2019), Materials Chemistry and Physics, 221: 89-98. https://www.sciencedirect.com/science/article/abs/pii/S0254058418307818

Rutherford, D, Exarhos, S, Xu, C, et al. Synthesis, characterization, and cytocompatibility of yttria stabilized zirconia nanopowders for creating a window to the brain. J Biomed Mater Res. 2020; 108B: 925– 938. https://doi.org/10.1002/jbm.b.34445

Video-based kinetic analysis of calcification in live osteogenic human embryonic stem cell cultures reveals the developmentally toxic effect of Snus tobacco extract. Ivann K.C. Martinez, Nicole R.L. Sparks, Joseph V. Madrid, Henry Affeldt, Madeline K.M. Vera, Bir Bhanu, Nicole I. zur Nieden, (2019), Toxicology and Applied Pharmacology, 363:111-121. https://pubmed.ncbi.nlm.nih.gov/30468815/

A Mitochondrial Stress Response in Neural Stem Cells Exposed to Electronic Cigarettes. Atena Zahedi, Rattapol Phandthong, Angela Chaili, Guadalupe Remark and Prue Talbot (2019), iScience, Vol 16, P250-269. https://doi.org/10.1016/j.isci.2019.05.034

Fabrication of centimeter-scale and geometrically arbitrary vascular networks using in vitro self-assembly. Morgan, J.T., Shirazi, J., Comber, E.M., Eschenburg, C., Gleghorn, J.P. (2019) Biomaterials, Volume 189, 2019, Pages 37-47. https://www.sciencedirect.com/science/article/pii/S014296121830735X

2018

Developmental Xist induction is mediated by enhanced splicing. Stork, C., Li, Z., Lin, L., Zheng, S. Nucleic Acids Res. 2018 Nov 29. doi: 10.1093/nar/gky1198.

Early specification and development of rabbit neural crest cells. Betters, E., Charney, R.M., Garcia-Castro, M.I., Developmental Biology, 2018 https://doi.org/10.1016/j.ydbio.2018.06.012

Dynamic blebbing: A bottleneck to human embryonic stem cell culture that can be overcome by laminin-Integrin signaling. Weng, N.J.H., Cheung, C., Talbot, P. (2018) Stem Cell Research, Volume 33, Pages 233-246. https://www.sciencedirect.com/science/article/pii/S1873506118302678

The Mechanosensitive Ion Channel TRPV4 is a Regulator of Lung Development and Pulmonary Vasculature Stabilization. Morgan, J.T., Stewart, W.G., McKee, R.A., Gleghorn, J.P., (2018) Cel. Mol. Bioeng.11: 309. https://link.springer.com/article/10.1007/s12195-018-0538-7

Epithelial-to-Mesenchymal Transition of A549 Lung Cancer Cells Exposed to Electronic Cigarettes.
Zahedi, A., Phandthong, R., Chaili, A., Lemark, G. & Talbot, P. Lung Cancer 122, 224–233 (2018). https://pubmed.ncbi.nlm.nih.gov/30032837/

Deep Analysis of Mitochondria and Cell Health Using Machine Learning.
Zahedi, A., On. V., Phandthong, R., Chaili, A., Remark, G., Bhanu, B., Talbot, P. Scientific Reports. 2018 Nov 5; 8(1):16354. https://www.nature.com/articles/s41598-018-34455-y

2017

Low, K., Wong, L. Y., Maldonado, M., Manjunath, C., Horner, C. B., Perez, M., … Nam, J. (2017). Physico-electrochemical Characterization of Pluripotent Stem Cells during Self-Renewal or Differentiation by a Multi-modal Monitoring System. Stem Cell Reports, 8(5), 1329–1339. https://doi.org/10.1016/j.stemcr.2017.03.021

Maldonado, M., Luu, R. J., Ico, G., Ospina, A., Myung, D., Shih, H. P., & Nam, J. (2017). Lineage- and developmental stage-specific mechanomodulation of induced pluripotent stem cell differentiation. Stem Cell Research & Therapy, 8(1), 216.http://doi.org/10.1186/s13287-017-0667-2

Nampe, D., Joshi, R., Keller, K., zur Nieden, N. I., & Tsutsui, H. (2017). Impact of fluidic agitation on human pluripotent stem cells in stirred suspension culture. Biotechnology and Bioengineering, 114(9), 2109–2120. http://doi.org/10.1002/bit.26334

Sparks, N. R. L., Martinez, I. K. C., Soto, C. H., & zur Nieden, N. I. (2017). Low Osteogenic Yield in Human Pluripotent Stem Cells Associates with Differential Neural Crest Promoter Methylation. Stem Cells, 36(3), 349–362. http://doi.org/10.1002/stem.2746

Weng, N. J.-H., & Talbot, P. (2017). The P2X7 receptor is an upstream regulator of dynamic blebbing and a pluripotency marker in human embryonic stem cells. Stem Cell Research, 23, 39–49. https://doi.org/10.1016/j.scr.2017.06.007

2015

Maricela Maldonado, Lauren Y. Wong, Cristina Echeverria, Gerardo Ico, Karen Low, Taylor Fujimoto, Jed K. Johnson, Jin Nam. The effect of electrospun substrate-mediated cell colony morphology on the self-renewal of human induced pluripotent stennm cells.Biomaterials 50 (2015) 10-19

Cipriano AF, Sallee A, Guan RG, Zhao ZY, Tayoba M, Sanchez J, Liu H.Investigation of magnesium-zinc-calcium alloys and bone stem cell response in direct culture.Acta Biomater. 2015 Jan 15;12:298-321

2014

Yang X, Scott HA, Ardekani S, Williams M, Talbot P, Ghosh K. Aberrant cell and basement membrane architecture contribute to sidestream smoke-induced choroidal endothelial dysfunction. Invest Ophthalmol Vis Sci. Apr 8;55(5):3140-7

Keller KC, Rodrigues B, zur Nieden NI. Suspension culture of pluripotent stem cells: effect of shear on stem cell fate. Crit Rev Eukaryot Gene Expr. 24(1):1-13

McClelland Descalzo DL, Ehnes DD, zur Nieden NI. Stem cells for osteodegenerative diseases: current studies and future outlook.Regen Med. Mar;9(2):219-30

Guan, B. X., B. Bhanu, P. Talbot, S. Lin. Bio-driven cell region detection in human embryonic stem cell assay. IEEE/ACM Transactions on Computational Biology and Bioinformatics, Jan 2014; 11(3):604-611

Lin, S.C., Talbot, P. Stem Cells. In: Wexler, P. (Ed.), Encyclopedia of Toxicology, 3rd edition vol 4. Elsevier Inc., Academic Press, pp. 390–394

Talbot, P. N. zur Nieden, S. Lin, I. Martinez, B. Guan and B. Bhanu. Use of video bioinformatics tools in stem cell biology. In: Handbook of Nanotoxicology, Nanomedicine and Stem Cell Use in Toxicology, Eds: S. Sahu and D. Casciano, John Wiley, West Sussex, United Kingdom. p 379-402

Sebaa M, Nguyen TY, Dhillon S, Garcia S, Liu H. The effect of poly (3, 4-ethylenedioxythiophene) (PEDOT) coating on magnesium degradation and cytocompatibility with hESCs for potential neural applications. J Biomed Mater Res A. Feb 23

Cipriano AF, De Howitt N, Gott SC, Miller C, Rao MP, Liu H. Bone Marrow stromal cell adhesion and morphology on micro-and sub-micropatterned titanium. J Biomed Nanotechnol Apr 10(4):660-8